Tricyclic benzazepine vasopressin antagonists

Details Tricyclic benzazepine vasopressin antagonists Tricyclic benzazepine vasopressin antagonists

1995-01-17

1996-05-28

Datlow, Philip I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540558, 540561, 540562, 544344, C07D48704, A61K 3155

Patent

active

055211739

ABSTRACT:
Tricyclic diazepines of the Formula I: ##STR1## wherein A, B, D, E, F, Y, and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.

REFERENCES:
patent: 3763183 (1973-10-01), Carabateas
patent: 4766108 (1988-08-01), Ali
patent: 5055448 (1991-10-01), Manning et al.
patent: 5070187 (1991-12-01), Gavras et al.
patent: 5258510 (1993-11-01), Ogawa et al.
J. Med. Chem., 1992, 35, 3905-3918, Williams et al.
J. Med. Chem., 1992, 35, 3895-3904--Manning et al.
J. Med. Chem., 1992, 35, 382-388, Manning et al.
From Vasopressin Antagonist to Agonist, DN+P4 (4), May 1991, Ruffolo et al., pp. 217-221.
Br. J. Pharmacol. (1992), 105, 787-791, Yamamura et al.
Science, vol. 252, pp. 572-574, Yamamura et al. (1991).
J. Med. Chem., 1992, 35, 3919-3927, Evans et al.
J. Med. Chem., 1993, 36, 3993-4005, Evans et al.

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