Tricyclic benzazepine vasopressin antagonists

Details Tricyclic benzazepine vasopressin antagonists Tricyclic benzazepine vasopressin antagonists

1997-06-13

1998-11-10

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540589, 540586, 540578, C07D48704, A61K 31395

Patent

active

058344616

ABSTRACT:
Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V.sub.1 and/or V.sub.2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and processes for preparing such compounds.

REFERENCES:
patent: 5512563 (1996-04-01), Albright et al.
Albright et al, Chemical Abstracts, vol. 123: entry 313792 (1995).

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