Tricyclic antipsychotic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514287, 546 65, 546 93, 546111, A61K 31435, C07D22106, C07D491056

Patent

active

052545610

ABSTRACT:
A class of 2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridine and 2,3,4,4a,5,6,7,11b-octahydro-1H-benzo[3,4]cyclohepta[1,2-c]pyridine derivatives are selective ligands at sigma recognition sites and are therefore useful in the treatment and/or prevention of psychiatric and/or gastrointestinal disorders.

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J. Med. Chem., 1978, 21, 340.
Julien, et al., Eur. J. Pharmacol., 1990, 183, 2145.
Pascaud, et al., J. Pharmacol. Exp. Ther., 1990, 255, 1354.

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