Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-06-18
1993-10-19
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514287, 546 65, 546 93, 546111, A61K 31435, C07D22106, C07D491056
Patent
active
052545610
ABSTRACT:
A class of 2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridine and 2,3,4,4a,5,6,7,11b-octahydro-1H-benzo[3,4]cyclohepta[1,2-c]pyridine derivatives are selective ligands at sigma recognition sites and are therefore useful in the treatment and/or prevention of psychiatric and/or gastrointestinal disorders.
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Julien, et al., Eur. J. Pharmacol., 1990, 183, 2145.
Pascaud, et al., J. Pharmacol. Exp. Ther., 1990, 255, 1354.
Billington David C.
Russell Michael G. N.
DiPrima Joseph F.
Ivy C. Warren
Merck Sharp & Dohme Limited
Nicholson William
North Robert J.
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