Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-04-19
1986-09-16
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
540101, 540110, A61K 31445, C07D22110
Patent
active
046123164
ABSTRACT:
Compounds of the formula ##STR1## wherein C.sup.1 and N.sup.4 are in trans configuration to each other, wherein R and Y are defined herein below, as bases and pharmaceutically acceptable acid addition salts thereof, processes for their preparation and pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for treatment of disorders in the central nervous system.
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Cannon, J., et al., Journal of Medicinal Chemistry, 1976, 19(8), pp. 987-993.
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Andersson Bengt R.
Arvidsson Folke L.
Carlsson Per A. E.
Hjort John S. M.
Johansson Anette M.
Astra Lakemedel Aktiebolag
Schwartz Richard A.
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