Tricyclic amides

Details Tricyclic amides Tricyclic amides

1997-10-01

1998-12-15

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514337, 514339, 514443, 514468, 5462767, 5462811, 5462841, 548436, 548437, 548438, 549 43, 549 44, 549 45, 549 47, 549458, A61K 3134, A61K 3140, C07D20956, C07D30777

Patent

active

058497811

ABSTRACT:
The invention relates to a compound selected from these of formula (I): ##STR1## in which R.sub.7, R.sub.8, Y, n and A are as defined in the description, and medicinal product containing the same useful for treating a disorder of the melatoninergic system.

REFERENCES:
patent: 5244911 (1993-09-01), Booher et al.
patent: 5244912 (1993-09-01), Booher et al.
patent: 5470853 (1995-11-01), Flaugh et al.
Pickering, et al. British Journal of Pharmacology 119, No. 2, pp. 379-387, Sep. 1996; "Analogs of diverse structure are unable to differentiate native melatonin receptors in the chicken retina, sheep parts tuuberalis and Xenopus melanophores".
Haefliger et al., Chemical Abstracts, vol. 98, abstract 126427, 1983.
Pickering et al., Chemical Abstracts, vol. 125, abstact 293301, 1996.
Spadoni et al., Chemical Abstracts, vol. 127, abstract 34048, 1997.
C. Evans et al., Reactions of 2,3-Dihydro-4-methylphenalen-1 one J. Chem. Soc. (C), 1971 pp. 1607-1609.
Wieringa et al., Chemical Abstracts, vol. 96, abstract 122465h (1982).
Heindl et al. Chemical Abstracts, vol. 106, abstract 1562272h (1987).

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