Tricyclic alkylamine derivatives

Details Tricyclic alkylamine derivatives Tricyclic alkylamine derivatives

1976-04-12

1978-12-05

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26032627, 2603265B, 2603269, 424274, C07D20986

Patent

active

041285603

ABSTRACT:
Tricyclic alkylamines, and their acid addition salts with pharmaceutically acceptable acids, are disclosed. The tricyclic ring system for these compounds is selected from the group consisting of 1,2,3,4-tetrahydrocyclopent[b]indole, 1,2,3,4-tetrahydrocarbazole and 5,6,7,8,9,10-hexahydrocyclohept[b]indole. The compounds are characterized further in that the ring system carbon atom bearing the alkylamine residue is carbon atom 3, 1 and 6 in the respective ring systems and in each case the said carbon atom also is substituted with a lower alkyl. The tricyclic alkylamines are useful antidepressant agents. Methods for their preparation and use are disclosed.

REFERENCES:
patent: 3769298 (1973-10-01), McManus et al.
patent: 3859304 (1975-01-01), Dostert et al.

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