Tricyclic 2-pyrimidone compounds useful as HIV reverse...

Details Tricyclic 2-pyrimidone compounds useful as HIV reverse... Tricyclic 2-pyrimidone compounds useful as HIV reverse...

2007-03-06

2007-03-06

Tucker, Zachary C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C514S267000

Reexamination Certificate

active

10891974

ABSTRACT:
The present invention relates to tricyclic 2-pyrimidone compounds of formula (I):or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

REFERENCES:
patent: WO 01/29037 (2001-04-01), None
patent: WO 01/29037 (2001-04-01), None
patent: WO 02/08226 (2002-01-01), None
Besly, et al., J. Chem. Soc., “Potential Antimalarial Derivatives of Triaza-anthracene”, pp. 4997-5001 (1957).
Levine, et al., J. Heterocyclic Chem., “Pyrimido[5,4-b]quinolines. II. Reactions at the Heterocyclic Ring-Carbon and Nitrogen Atoms (1)”, pp. 611-614 (1977), (14).
Levine, et al., J. Heterocyclic Chem., “Pyrimido[5,4-b]quinolines. I. Synthesis of Substituted Tricyclic Systems Related to Riboflavin (1a).”, pp. 91-97 (1972), (9)1.
O'brien, et al., J. Heterocyclic Chem., “Synthesis of 10-Deazariboflavin and Related 2,4-Dioxopyrimido[4,5-b[quinolines (1a)”, pp. 99-102 (1970) (7).
Chu, et al., J. Heterocyclic Chem., “Pyrimido[5,4-b] quinolines. III. Synthesis of a 10-Alkyl-Substituted 10-Deazaalloxazines (1a)”, pp. 1053-1057 (1977).
Fenner, et al., Arch. Pharm., “Pyrimido[5,4-b]chinoline-10-Deaza-alloxazine”, pp. 115-125, (1978).
Fenner, et al., “Pyrimido[4,5-c] quinolines from 10-Cyanopyrimido[5,4-b]quinolines”, Arch. Pharm., pp. 382-384 (1986), (319)4.
Fenner, et al., “Pyrimido[5,4-b]quinolines by Trialkylphosphite-Cyclisation of 2-Nitro-6′-benzylpyrimidindiones”, Arch.Pharm., pp. 379-381 (1986), (319)4.

Affiliated with

Also associated with

Rating

Tricyclic 2-pyrimidone compounds useful as HIV reverse... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tricyclic 2-pyrimidone compounds useful as HIV reverse..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tricyclic 2-pyrimidone compounds useful as HIV reverse... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3741987