Tricyclic 2-pyrimidone compounds useful as HIV reverse...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S267000, C544S234000, C544S249000, C544S250000, C544S251000

Reexamination Certificate

active

06844340

ABSTRACT:
The present invention relates to tricyclic 2-pyrimidone compounds of formula (I):or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

REFERENCES:
patent: WO 0129037 (2001-04-01), None
patent: WO 0208226 (2002-01-01), None
Britikova, N.E. et al., “Some Derivatives of pyrimido[5,4-b]quinoline”, Khim. Geterotsikl. Soedin., pp. 117-119 (1974) (English translation of Khim. Geterotsikl. Soedin., No. 1, pp. 131-133 (1974)).
Britikova, N.E. et al., “Study of Nucleophilic Substitution Reactions of 2,4,10-trichloropyrimido[5,4-b]quinoline”, Khim. Geterotsikl. Soedin., pp. 482-484 (1974) (English translation of Khim. Geterotsikl. Soedin., No. 4, pp. 554-557 (1974)).
Ueda, et al., “Transformation of Pyrazolo[3,4-c][1,5]benzothiazepines into Quinolines”, Chem. Pharm. Bull., pp. 1604-1607, (1984), (32)4.
Besly, et al., J. Chem. Soc., “Potential Antimalarial Derivatives of Triaza-anthracene”, pp. 4997-5501 (1957).
Levine, et al., J. Heterocyclic Chem., “Pyrimido[5,4-b]quinolines, II. Reactions at the Heterocyclic Ring-Carbon and Nitrogen Atoms (1)”, pp. 611-614 (1974), (14).
Levine, et al., J. Heterocylic Chem., “Pyrimido[5,4-b]quinolines. I. Synthesis of Substituted Tricyclic Systems Related to Riboflavin (1a).”, pp. 91-97 (1972), (9)1.
O'brien, et al., J. Heterocylic Chem., “Synthesis of 10-Deazariboflavin and Related 2,4-Dioxopyrimido[4,5-b]quinolines (1a)”, pp. 99-102 (1970) (7).
Chu, et al., J. Heterocylic Chem., “Pyrimido[5,4-b] quinolines. III. Synthesis of a 10-Alkyl-Substitued 10-Deazaalloxazines (1a)”, pp. 1053-1057 (1977).
Fenner, et al., Arch. Pharm., “Pyrimido[5,4-b]chinoline-10-Deaza-alloxazine”, pp. 115-125, (1978).
Fenner, et al., “Pyrimido[4,5-c] quinolines from 10-Cyanopyrimido[5,4-b]quinolines”, Arch. Pharm., pp. 382-384 (1986), (319)4.
Fenner, et al., “Pyrimido[5,4-b]quinolines by Trialkylphosphite-Cyclisation of 2-Nitro-6′-benzylpyrimidindiones”, Arch.Pharm., pp. 379-381 (1986), (319)4.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tricyclic 2-pyrimidone compounds useful as HIV reverse... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tricyclic 2-pyrimidone compounds useful as HIV reverse..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tricyclic 2-pyrimidone compounds useful as HIV reverse... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3417033

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.