Triclosan and silver compound containing medical devices

Details Triclosan and silver compound containing medical devices Triclosan and silver compound containing medical devices

2005-01-18

2005-01-18

Kennedy, Sharon (Department: 3762)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C424S422000, C428S035700

Reexamination Certificate

active

06843784

ABSTRACT:
The present invention relates to polymeric medical articles comprising combinations of triclosan and silver-containing compounds. It is based, at least in part, on the discovery that these agents act synergistically, thereby permitting the use of relatively low levels of both agents. While it had been previously found that triclosan can be particularly useful when used in conjunction with chlorhexidine, it has been further discovered that medical articles having suitable antimicrobial properties may be prepared, according to the present invention, which contain triclosan without chlorhexidine. Such medical articles offer the advantage of preventing or inhibiting infection while avoiding undesirable adverse reactions to chlorhexidine by individuals that may have sensitivity to chlorhexidine.

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The Merck Index, An Encyclopedia of Chemicals, Drugs and Biologicals, Tenth Edition (Merck & Co., Inc., Rahway, NJ, 1983), p. 1092.

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