Chemistry: molecular biology and microbiology – Vector – per se
Patent
1993-04-30
1997-04-01
Jacobson, Dian C.
Chemistry: molecular biology and microbiology
Vector, per se
435 691, 435193, 435325, 435348, 536 221, 536 231, 536 232, 536235, 536 243, 536 2431, 536 2433, C12N 1500, C12P 2106, C12H 910, C07H 1900
Patent
active
056165005
ABSTRACT:
The sequences of a pair of human proteins, trichohyalin and transglutaminase-3, in addition to the sequence of the mouse transglutaminase-3 protein, have been discovered. The enzyme transglutaminase-3 is used to cross-link the structural protein trichohyalin in order to form a gel.
REFERENCES:
Kim et al. "The Deduced Sequence of the Novel Protransglutaminase . . . " J.B.C. 268:17 pp. 12682-12690 1993.
Kim et al. "The Complete Amino Acid Sequence . . . " J.B.C. 266:1 pp. 536-539 1991.
Kim et al. "Protransglutaminase E . . . " J.B.C. 265:35 pp. 21971-21978 1990.
Lee et al. "Generation of cDNA Probes . . . " Science 239:1288-1291 1988.
Park, et al., "Expression of Transglutaminase E in Cultured Human Keratinocytes and Skin Tissues", Progress in Clinical Biochemistry, pp. 275-278, 1992.
Kim, et al., "The Deduced Sequence of the Novel Protransglutaminase E (TGase3) of Human and Mouse", Journal of Biological Chemistry, vol. 268, No. 17, pp. 12682-12690, Jun. 15, 1993.
Lee, et al., "The Structure of Human Trichohyalin", Journal of Biological Chemistry, vol. 268, No. 16, pp. 12164-12178, Jun. 5, 1993.
Chung Soo-Il
Kim In-Gyu
Park Sang-chul
Steinert Peter M.
Jacobson Dian C.
Kim Hyosuk
The United States of America as represented by the Department of
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