Trichoderma promoter

Details Trichoderma promoter Trichoderma promoter

2008-08-18

2011-10-25

Joike, Michele (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S254110, C435S071100

Reexamination Certificate

active

08044192

ABSTRACT:
A promoter for use in producing proteins in filamentous fungal host cells is provided. In one embodiment, the promoter comprises SEQ ID NO:1, or a variant or a truncated form thereof that has promoter activity in a host cell. Also provided are recombinant nucleic acids, vectors containing the promoter and host cells containing a recombinant nucleic acid or vector. Methods of producing a protein using the host cells are also provided.

REFERENCES:
patent: 5364770 (1994-11-01), Berka et al.
patent: 5989870 (1999-11-01), Nakari et al.
patent: 6001595 (1999-12-01), Ilmén et al.
patent: 6022725 (2000-02-01), Fowler et al.
patent: 6103490 (2000-08-01), Berka et al.
patent: 6268328 (2001-07-01), Mitchinson et al.
patent: 6509171 (2003-01-01), Berka et al.
patent: 6562612 (2003-05-01), Jones et al.
patent: 6590078 (2003-07-01), Ward et al.
patent: 0 215 594 (1987-03-01), None
patent: 0 244 234 (1987-11-01), None
patent: 0 351 029 (1990-01-01), None
patent: WO 96/00787 (1996-01-01), None
patent: WO 01/51643 (2001-07-01), None
patent: WO 03/089621 (2003-10-01), None
patent: WO 2005/001036 (2005-01-01), None
patent: WO 2006/060062 (2006-06-01), None
patent: WO 2008/076322 (2008-06-01), None
Henrique-Silva et al. Two Regulatory Regions Controlling Basal and Cellulose-Induced Expression of the Gene Encoding Cellobiohydrolase I of Trichoderma Adjacent to Its TATA Box. Biochemical and Biophysical Research Communications vol. 228, Issue 2, Nov. 12, 1996, pp. 229-237.
U.S. Appl. No. 10/992,187, filed Sep. 22, 2005, Baldwin et al.
U.S. Appl. No. 11/255,794, filed Feb. 23, 2006, Stafford et al.
U.S. Appl. No. 11/108,088, filed Feb. 23, 2006, Davidson et al.
U.S. Appl. No. 60/984,430, filed Nov. 1, 2007, Bao et al.
Altschul, S.F. et al. “Basic local alignment search tool.”J. Mol. Biol215(3): 403-410, 1990.
Bagdasarian, M.M. et al. “Activity of the hybrid trp-lac (tac) promoter ofEscherichia coliinPseudomonas putida. Construction of broad-host-range, controlled-expression vectors.”Gene26(2-3): 273-282, Dec. 1983.
Berka, R.M. et al. “Aspergillus nigervar.awamorias a host for the expression of heterologous genes.” InApplications of Enzyme Biotechnology, edited by J.W. Kelly et al., pp. 273-292. New York: Plenum Press, 1991.
Berka, R.M. et al. “Molecular cloning and deletion of the gene encoding aspergillopepsin A fromAspergillus awamori.” Gene86(2): 153-162, Feb. 14, 1990.
Bower, B. et al. “Hyperexpression and glycosylation ofTrichoderma reeseiEG III.” inCarbohydrases from Trichoderma reesei and other micro-organisms, edited by M. Claeyssens et al., pp. 327-334. Cambridge, England: Royal Society of Chemistry, 1998.
Campbell, E.I. et al. “Improved transformation efficiency ofAspergillus nigerusing the homologous niaD gene for nitrate reductase.”Current Genetics16(1): 53-56, Jul. 1, 1989.
Cao, Q.N. et al. “Penicillopepsin-JT2, a recombinant enzyme fromPenicillium janthinellumand the contribution of a hydrogen bond in subsite S3 to k(cat).”Protein Sci9(5): 991-1001, May 1, 2000.
Chambergo F.S. et al. “Elucidation of the metabolic fate of glucose in the filamentous fungusTrichoderma reeseiusing expressed sequence tag (EST) analysis and cDNA microarrays”Journal of Biological Chemistry, 227(16):13983-13988, Apr. 19, 2002.
Database EMBL [Online], Nov. 1, 2003 “tric083xm17.b11T. reesei mycelialculture, version 6 Oct. 2003Hypocrea jecorinacDNA clone tric083xm17, mRNA sequence.” retreived from EBI accession No. EMBL: CF885793.
Database Geneseq [Online], Mar. 13, 2001 “Trichoderma reeseiest seq ID No. 7499”, retrieved from EBI accession No. GSN: AAF14976.
Database JGIT. reeseiv1.0 [Online], Joint Genome Institute; version 1.5.4 Jun. 1, 2007, “T. reeseiv.1.0” XP 002506721 retrieved from http://genome.JGI-psf.org/CGI-bin/dispgene model?db=trire1&tid=43977 accession No. protein ID: 43977 Database accession No. estExt—fgenesh1-pg.C—30027.
Deuschle, U. et al. “Promoters ofEscherichia coli: a hierarchy of in vivo strength indicates alternate structures.”The EMBO Journal5(11): 2987-2994, Nov. 1986.
Diener S.E. et al. “Characterization of the protein proessing and secretion pathways in a comprehensive set of expressed sequence tags fromTrichoderma reesei” Fems Microbiology Letters, 230(2): 275-282, Jan. 30, 2004.
Foreman, P.K. et al. “Transcriptional Regulation of Biomass-degrading Enzymes in the Filamentous FungusTrichoderma reesei.” J. Biol. Chem. 278(34): 31988-31997, Aug. 22, 2003.
Harkki, A. et al. “Genetic engineering ofTrichodermato produce strains with novel cellulase profiles.”Enzyme Microb. Technol13(3): 227-33, Mar. 1991.
Harkki, A. et al. “A Novel Fungal Expression System: Secretion of Active Calf Chymosin from the Filamentous FungusTrichoderma reesei.” Bio/Technology7(6): 596-603, Jun. 1989.
Hopwood, D.A. et al. “Regulation of gene expression in antibiotic-producingStreptomyces.” InRegulation of gene expression—25 years on, edited by I.R. Booth et al., pp. 251-276. Cambridge, England: Cambridge UP, 1986.
Ilmén, M. et al. “Regulation of cellulase gene expression in the filamentous fungusTrichoderma reesei.” Applied and Environmental Microbiology63(4): 1298-306, Apr. 1997.
Innis, M. A. et al. “Expression, Glycosylation, and Secretion of anAspergillusGlucoamylase bySaccharomyces cerevisiae.” Science228(4695): 21-26, Apr. 5, 1985.
Karlin, S. et al. “Applications and statistics for multiple high-scoring segments in molecular sequences.”Proc. Natl. Acad. Sci. USA90(12): 5873-7, Jun. 15, 1993.
Kelly, J.M. et al. “Transformation ofAspergillus nigerby the amdS gene ofAspergillus nidulans.” EMBO J. 4(2): 475-479, Feb. 1985.
Keranen, Sirkka et al. “Production of recombinant proteins in the filamentous fungusTrichoderma reesei” Current Opinion in Biotechnology, London, GB, 6(5): 534-537Jan. 1, 1995.
Labes, G. et al. “Isolation and characterization of a strong promoter element from theStreptomyces ghanaensisphage I19 using the gentamicin resistance gene (aacC1) of Tn 1696 as reporter.”Microbiology(Reading, England) 143(Pt. 5): 1503-12, May 1997.
Mach, R.L. et al. “Regulation of gene expression in industrial fungi:Trichoderma.” Applied microbiology and biotechnology60(5) : 515-522, Jan. 2003.
Machida, M. et al. “Genome sequencing and analysis ofAspergillus oryzae.” Nature438(7071): 1157-61, 2005.
Nakamura, Y. et al. “Codon usage tabulated from international DNA sequence databases: status for the year 2000.”Nucl. Acids Res. 28(1): 292, Jan. 1, 2000.
Needleman, S.B. et al. “A general method applicable to the search for similarities in the amino acid sequence of two proteins.”J. Mol. Biol48(3): 443-53, Mar. 1970.
Nevalainen, K.M.H. et al. “The Molecular Biology ofTrichodermaand its Application to the Expression of Both Homologous and Heterologous Genes.” InMolecular Industrial Mycology, edited by S.A. Leong et al., pp. 129-148. New York: Marcel Dekker, 1991.
Nunberg, J.H. et al. “Molecular cloning and characterization of the glucoamylase gene ofAspergillus awamori.” Mol. Cell. Biol. 4(11): 2306-2315, Nov. 1, 1984.
Paloheimo, M. et al. “High-Yield Production of a Bacterial Xylanase in the Filamentous FungusTrichoderma reeseiRequires a Carrier Polypeptide with an Intact Domain Structure.”Appl. Environ. Microbiol. 69(12): 7073-7082, Dec. 1, 2003.
Pearson, W.R. et al. “Improved Tools for Biological Sequence Comparison.”Proc. Natl. Acad. Sci. USA85(8): 2444-2448, Apr. 15, 1988.
Penttilä, M. et al. “A versatile transformation system for the cellulolytic filamentous fungusTrichoderma reesei.” Gene61(2): 155-64, 1987.
Pourquié, J. et al. “Scale up of cellulase production and utilization.” InBiochemistry and Genetics of Cellulose De

Affiliated with

Also associated with

Rating

Trichoderma promoter does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Trichoderma promoter, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trichoderma promoter will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4292573