Triazolo-benzodiazepine derivatives

Details Triazolo-benzodiazepine derivatives Triazolo-benzodiazepine derivatives

1981-01-16

1983-02-22

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602444, 2602393D, 424267, 424269, 564195, 564328, A61K 3155, C07D48704

Patent

active

043747736

ABSTRACT:
There are presented compounds of the formula ##STR1## wherein R.sup.1 is a hydrogen atom or a lower alkyl group, R.sup.2 and R.sup.3 each are a hydrogen atom or a lower alkyl group, R.sup.4 is a halogen atom and either R.sup.5 is a hydrogen atom or a lower alkyl group and R.sup.6 is a lower alkyl or lower hydroxyalkyl group or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are attached are a 3-membered to 7-membered heterocycle,
and pharmaceutically acceptable acid addition salts thereof.
The compounds and their salts are novel and possess valuable pharmacodynamic properties.

REFERENCES:
patent: 4251443 (1981-02-01), Fischli et al.
Moffett, Letters on Heterocyclic Chemistry, vol. III, pp. S-123-129 (1976).

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