Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1983-03-03
1984-10-16
Raymond, Richard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242484, 42424852, 424251, 544 582, 544 61, 544118, 544122, 544263, 544295, 544317, 544328, A61K 31535, A61K 3154, C07D48704
Patent
active
044774508
ABSTRACT:
1,2,4-Triazolo[4,3-c]pyrimidines substituted at the 5 or 7 position through a nitrogen atom which is part of a heterocyclic ring have been found to have potent bronchodilator activity and to be useful synthetic intermediates in the preparation of 1,2,4-triazolo[1,5-c]-pyrimidines. Methods for inducing bronchodilation, pharmaceutical compositions, and synthetic processes and intermediates are also described.
REFERENCES:
patent: 4269980 (1981-05-01), Hardy et al.
G. W. Miller et al., J. Chem. Soc., 1963, 5642.
G. W. Miller et al., J. Chem. Soc., 1963, 3357.
W. Broadbent et al., J. Chem. Soc., 1963, 3369.
Shiho, et al., Yakagaku Zasshi, 1956, 76, 804 (Japanese text).
Temple, et al., J. Org. Chem. 1968, 33, 530.
D. J. Brown et al., Aust. J. Chem. 1978, 31, 2505.
D. J. Brown et al., Aus. J. Chem., 1979, 32, 1585.
Raymond Richard
Riker Laboratories Inc.
Sell Donald M.
Smith James A.
Sprague Robert W.
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