Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-02-01
2005-02-01
Powers, Fiona T. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S311000, C514S340000, C514S364000, C514S365000, C514S383000, C544S333000, C546S167000, C546S272400, C548S131000, C548S203000, C548S266200, C548S266400, C548S266800, C548S267200, C548S267800, C548S269400
Reexamination Certificate
active
06849636
ABSTRACT:
Triazole derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.
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Walker, Brian, R., “11β-Hydroxysteroid dehydrogenase Type 1 as a novel therapeutic target in metabolic and neurodegenerative disease”, Expert Opinion Therapeutic Targets, vol. 7(6), pp. 771-783 (2003).
Aster Susan D.
Balkovec James M.
Graham Donald W.
Gu Xin
Leeman Aaron H.
Billups Richard C.
Durette Philippe L.
Powers Fiona T.
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