Triazole derivatives as inhibitors of 11-beta-hydroxysteroid...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S215000, C548S262200

Reexamination Certificate

active

07932280

ABSTRACT:
Triazole derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.

REFERENCES:
patent: 6849636 (2005-02-01), Waddell et al.
patent: 2005/0070720 (2005-03-01), Balkovec et al.

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