Triazole compounds that modulate HSP90 activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S384000, C514S422000, C514S326000, C514S269000, C514S231500, C544S060000, C544S132000, C544S366000, C546S210000, C548S262200, C548S263200, C548S263800, C548S264600, C548S518000

Reexamination Certificate

active

07662813

ABSTRACT:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

REFERENCES:
patent: 3189614 (1965-06-01), Pesson
patent: 4178253 (1979-12-01), Lee et al.
patent: 4269846 (1981-05-01), Huang et al.
patent: 4624995 (1986-11-01), Katritzky et al.
patent: 4740568 (1988-04-01), Katritzky et al.
patent: 4931084 (1990-06-01), Kindeisen et al.
patent: 5006650 (1991-04-01), Barbachyn
patent: 5219722 (1993-06-01), Tanaka et al.
patent: 5298520 (1994-03-01), Baker et al.
patent: 5371101 (1994-12-01), Itoh et al.
patent: 5395818 (1995-03-01), Haas et al.
patent: 5436252 (1995-07-01), Sorensen et al.
patent: 5464810 (1995-11-01), Haas et al.
patent: 5466820 (1995-11-01), Itoh et al.
patent: 5476946 (1995-12-01), Linker et al.
patent: 5489598 (1996-02-01), Connor et al.
patent: 5510362 (1996-04-01), Matassa et al.
patent: 5532378 (1996-07-01), Daum et al.
patent: 5538988 (1996-07-01), Martinez et al.
patent: 5552369 (1996-09-01), Findeisen et al.
patent: 5625074 (1997-04-01), Daum et al.
patent: 5654438 (1997-08-01), Findeisen et al.
patent: 5663362 (1997-09-01), Haas et al.
patent: 5861358 (1999-01-01), Findeisen et al.
patent: 5869509 (1999-02-01), Romine et al.
patent: 5888694 (1999-03-01), Yamada et al.
patent: 5952502 (1999-09-01), McCullough et al.
patent: 5968921 (1999-10-01), Gold
patent: 5972844 (1999-10-01), Müller et al.
patent: 6077861 (2000-06-01), Romine et al.
patent: 6180567 (2001-01-01), Müller et al.
patent: 6194090 (2001-02-01), Okada
patent: 6200931 (2001-03-01), Müller et al.
patent: 6200934 (2001-03-01), Müller et al.
patent: 6251831 (2001-06-01), Müller et al.
patent: 6258957 (2001-07-01), Linker et al.
patent: 6271249 (2001-08-01), Romine et al.
patent: 6492406 (2002-12-01), Karabelas et al.
patent: 6583090 (2003-06-01), Gewehr et al.
patent: 6677277 (2004-01-01), Schallner et al.
patent: 6946456 (2005-09-01), Rosen et al.
patent: 7473784 (2009-01-01), Liu et al.
patent: 2003/0054996 (2003-03-01), Nicchitta et al.
patent: 2003/0216369 (2003-11-01), Rosen et al.
patent: 2003/0216385 (2003-11-01), Tobe et al.
patent: 2004/0063610 (2004-04-01), Gold
patent: 2004/0082498 (2004-04-01), Strehlow
patent: 2004/0110662 (2004-06-01), Rosen et al.
patent: 2004/0110684 (2004-06-01), Balligand et al.
patent: 2004/0214818 (2004-10-01), Tobe et al.
patent: 2004/0235813 (2004-11-01), Wanker et al.
patent: 2004/0266746 (2004-12-01), Rosen et al.
patent: 2005/0020534 (2005-01-01), Johnson, Jr., et al.
patent: 2005/0020556 (2005-01-01), Johnson, Jr., et al.
patent: 2005/0020557 (2005-01-01), Johnson, Jr., et al.
patent: 2005/0020558 (2005-01-01), Johnson, Jr., et al.
patent: 2005/0026893 (2005-02-01), Johnson, Jr., et al.
patent: 2005/0054589 (2005-03-01), Johnson, Jr., et al.
patent: 2005/0054625 (2005-03-01), Johnson, Jr., et al.
patent: 2005/0058956 (2005-03-01), Watanabe et al.
patent: 2005/0154039 (2005-07-01), Glacera et al.
patent: 2005/0288347 (2005-12-01), Hogle et al.
patent: 2006/0167070 (2006-07-01), Ying et al.
patent: 2006/0235058 (2006-10-01), Cheung et al.
patent: 2007/0087998 (2007-04-01), Ying et al.
patent: 2007/0191445 (2007-08-01), Ying et al.
patent: 2008/0004266 (2008-01-01), Du et al.
patent: 2008/0004276 (2008-01-01), Foley et al.
patent: 2008/0004277 (2008-01-01), Chimmanamada et al.
patent: 2008/0027047 (2008-01-01), Ying
patent: 2008/0090887 (2008-04-01), Ying et al.
patent: 2008/0176840 (2008-07-01), Sun et al.
patent: 10 2005 007 304 (2006-08-01), None
patent: 1 857 446 (2007-11-01), None
patent: 2 546 887 (1983-05-01), None
patent: 5010574 (1984-01-01), None
patent: 59010574 (1984-01-01), None
patent: 2000284412 (2000-10-01), None
patent: 2003114488 (2003-04-01), None
patent: WO 97/03067 (1997-01-01), None
patent: WO 98/04135 (1998-02-01), None
patent: WO 98/27092 (1998-06-01), None
patent: WO 00/42036 (2000-07-01), None
patent: WO 2002/36171 (2002-05-01), None
patent: WO 02/069972 (2002-09-01), None
patent: WO 2002/069900 (2002-09-01), None
patent: WO 2003/013430 (2003-02-01), None
patent: WO 03/045926 (2003-06-01), None
patent: WO 2003/050295 (2003-06-01), None
patent: WO 03/055860 (2003-07-01), None
patent: WO 2003/082266 (2003-10-01), None
patent: WO 2003/089006 (2003-10-01), None
patent: WO 2004/050087 (2004-06-01), None
patent: WO 2004/056782 (2004-07-01), None
patent: WO 2004/072051 (2004-08-01), None
patent: WO 2004/081037 (2004-09-01), None
patent: WO 2004/082676 (2004-09-01), None
patent: WO 2004/089367 (2004-10-01), None
patent: WO 2004/089415 (2004-10-01), None
patent: WO 2004/089416 (2004-10-01), None
patent: WO 2004/096212 (2004-11-01), None
patent: WO 2004/096781 (2004-11-01), None
patent: WO 2005/000300 (2005-01-01), None
patent: WO 2005/016920 (2005-02-01), None
patent: WO 2005/019184 (2005-03-01), None
patent: WO 2005/027972 (2005-03-01), None
patent: WO 2005/039569 (2005-05-01), None
patent: WO 2005/040345 (2005-05-01), None
patent: WO 2005/041879 (2005-05-01), None
patent: WO 2005/044194 (2005-05-01), None
patent: WO 2005/082866 (2005-09-01), None
patent: WO 2005/087750 (2005-09-01), None
patent: WO 2005/097758 (2005-10-01), None
patent: WO 2006/018082 (2006-02-01), None
patent: WO 2006/039977 (2006-04-01), None
patent: WO 2006/055760 (2006-05-01), None
patent: WO 2006/055760 (2006-05-01), None
patent: WO 2006/080533 (2006-08-01), None
patent: WO 2006/087077 (2006-08-01), None
patent: WO 2006/091246 (2006-08-01), None
patent: WO 2006/095783 (2006-09-01), None
patent: WO 2006/101052 (2006-09-01), None
patent: WO 2007/021877 (2007-02-01), None
patent: WO 2007/094819 (2007-08-01), None
patent: WO 2007/111904 (2007-10-01), None
patent: WO 2007/134678 (2007-11-01), None
patent: WO 2007/139951 (2007-12-01), None
patent: WO 2007/139952 (2007-12-01), None
patent: WO 2007/139955 (2007-12-01), None
patent: WO 2007/139960 (2007-12-01), None
patent: WO 2007/139967 (2007-12-01), None
patent: WO 2007/140002 (2007-12-01), None
patent: WO 2008/097640 (2008-01-01), None
patent: WO 2008/021364 (2008-02-01), None
patent: WO 2008/041610 (2008-04-01), None
patent: WO 2008/051416 (2008-05-01), None
patent: WO 2008/057246 (2008-05-01), None
patent: WO 2008/103353 (2008-08-01), None
patent: WO 2008/112199 (2008-09-01), None
patent: WO 2008/118391 (2008-10-01), None
patent: WO 2008/153730 (2008-12-01), None
patent: WO 2009/023211 (2009-02-01), None
U.S. Appl. No. 11/282,199.
Vippagunta et al., Advanced Drug Delivery Reviews, p. 1.
Andotra, C.S., et al. “Bridghead Nitrogen Heterocycles: Synthesis and Evaluation of Antibacterial, Antifungal Activities of Some 2-Substituted aryl-6-p-chlorophenyl-5-thione(1H)-1,2,4-5triazolo-[1,5-a]-s-triazin-7-ones,”Indian Journal of Heterocyclic Chemistry, 8(2); 139-142 (Oct.-Dec. 1998).
Ciugureanu, et al., “Biological Effects of Some New Thiosemicarbazides and Their Derivatives With Triazole and Thiadiazole Rings. II. Testing of Antifungal Effect,”Farmacia30(1):49-56 (1982).
Colanceska-Ragenovic, K., et al., “Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1, 2, 4-Triazoles,”Molecules6(9):815-824 (Sep. 2001).
Cowen, L.E., et al., “HSP90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi,”Science309: 2185-2189 (Sep. 2005).
Dogan, H.N., et al., “Synthesis, Structure Elucidation and Antimicrobial Activity of Some 3-Hydroxy-2-Naphthoic Acid Hydrazide Derivatives,”Farmaco53(7):462-467 (Jul. 30, 1998).
Larsen, S.D., et al., “Traceless Solid-Phase Synthesis of 1,2,4-Triazoles Using a Novel Amine Resin,”, 3(21):3341-3344 (Sep. 2001).
Yu, X.M., et al., “Synthesis of (-)-Noviose From 2, 3-0-Isopropylidence-D-Erythronolactol,”J. Org. Chem.69(21):7375-7378 (

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Triazole compounds that modulate HSP90 activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triazole compounds that modulate HSP90 activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triazole compounds that modulate HSP90 activity will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4152750

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.