Triazole compounds and the therapeutic use thereof

Details Triazole compounds and the therapeutic use thereof Triazole compounds and the therapeutic use thereof

2004-02-05

2008-12-16

Davis, Zinna N (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S383000, C546S148000, C548S266400

Reexamination Certificate

active

07465744

ABSTRACT:
The invention relates to triazole compounds of general formula (I), wherein A, B, R1, R2, R3and R4have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the use of the compound (I) for producing a pharmaceutical agent for treating illnesses, responding to the effects of dopamine-D3-receptor antagonists or dopamine-D3-receptor agonists, especially for treating disorders in the central nervous system.

REFERENCES:
patent: 6124294 (2000-09-01), Hellendahl et al.
patent: 6214822 (2001-04-01), Treiber et al.
patent: 6472392 (2002-10-01), Starck et al.
patent: 6579892 (2003-06-01), Starck et al.
patent: 44 25 144 (1999-01-01), None
patent: WO 97/25324 (1996-01-01), None
patent: WO 99/02503 (1997-07-01), None
patent: WO 00/42036 (2000-07-01), None
Levant, The D3 Dopamine Receptor: Neurobiology and Potential Clinical Relevance, Pharmacological Reviews, vol. 49, No. 3, pp. 231-252, 1997.
J C Schwartz et al. “The Dopamine D3 Receptor As A Target For Antipsychotics” Novel Antipsychotic Drugs, New York 1992, pp. 135-144.
Mukta Dooley et al “Pramipexole” Drugs & Aging, Jun. 1998, vol. 12, pp. 495-514.
J N Joyce et al “Dopamine D3 Receptor As A Therapeutic Target For Antipsychotic And Antiparkinsonian Drugs” Pharmacology & Therapeutics, 2001, vol. 90 pp. 231-259.
P Sokoloff et al. “Localization And Function Of The D3 Dopamine Receptor” Drug and Research 1992, vol. 42(1) No. 2a, pp. 224-230.
P Sokoloff et al “Molecular Cloning And Characterization Of A Novel Dopamine Receptor (D3) As A Target For Neuroleptics” Nature Sep. 13, 1990, vol. 347, pp. 146-151.

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