Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-02-09
1977-06-07
Ford, John M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602475C, 424249, C07D25308, C07D48704
Patent
active
040283569
ABSTRACT:
Compounds of formula IV: ##STR1## wherein R and R.sub.2 are hydrogen or methyl; wherein R.sub.1 is --COOH, --COOR' in which R' is alkyl of 1 to 3 carbon atoms, inclusive, --(CnH.sub.2 n)A in which n is an integer of 1 to 3 and A is fluoro, chloro, bromo, trifluoromethyl, hydroxy, alkoxy, in which the alkyl group is defined as above, or ##STR2## in which R" and R'" are hydrogen or alkyl as defined above or together ##STR3## is pyrrolidino, piperidino, morpholino, 4-methylpiperazino, 4-(2-hydroxyethyl)-piperazino; wherein R.sub.3 is hydrogen, fluoro, chloro, bromo, trifluoromethyl, or nitro; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, 2,6-difluorophenyl, or 2-pyridyl, are produced.
The compounds of formula IV of this invention are sedatives, tranquilizers and muscle-relaxants and can be used for such purposes in mammals and birds.
REFERENCES:
patent: 3818003 (1974-06-01), Szmuszkovicz
patent: 3933816 (1976-01-01), Szmuszkovicz
Berneis Hans L.
Ford John M.
The Upjohn Company
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