Triazine derivatives and their application as antitelomerase...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S198000, C544S209000

Reexamination Certificate

active

06887873

ABSTRACT:
The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.

REFERENCES:
patent: 5854244 (1998-12-01), Jarman et al.
patent: 6262053 (2001-07-01), Uckun et al.
patent: 11-60573 (1999-03-01), None
patent: WO 9940087 (1999-08-01), None
patent: WO 0140218 (2001-06-01), None
Chen et al., Spectroscopic Recognition of Guanine Dimeric Hairpin Quadruplexes by a Carbocyanine Dye,Proc. Natl. Acad. Sci. USA, 93: 2635-2639, 1996.
Kreutzberger et al., Synthesis and Spectroscopic Analyses of Dianilinotriazines,Chemiker-Zeitung, 114: 208-210, 1990. (English-language translation provided.).
Sun, et al., Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound,Journal of Medicinal Chemistry, 40: 2113-2116, 1997.
Wheelhouse et al., Cationic Porphyrins as Telomerase Inhibitors: The Interaction of Tetra-(N-methyl-4-pyridy) Porphine with Quadruplex DNA,J. Am. Chem. Soc., 120: 3261-3262, 1998.

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