Triazine derivatives

Details Triazine derivatives Triazine derivatives

1989-04-28

1991-01-15

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544182, C07D253075, A61K 3153

Patent

active

049854275

ABSTRACT:
Compounds of formula (I) ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen, halogen, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, phenylC.sub.1-3 alkoxy (in which the phenyl group is optionally substituted by a substituent selected from halogen, C.sub.1-3 alkyl, C.sub.1-3 alkoxy and hydroxy), nitro, trifluoromethyl, cyano, --CO.sub.2 R.sup.3 (wherein R.sup.3 is selected from hydrogen and C.sub.1-4 alkyl) and --CONR.sup.4 R.sup.5 (wherein R.sup.4 and R.sup.5 are each independently selected from hydrogen and C.sub.1-4 alkyl, or R.sup.4 and R.sup.5 together with the nitrogen atom to which they are attached form a saturated 5- to 7- membered ring, which ring optionally contains one or more groups or atoms selected from oxygen, sulphur, --NH-- and --N(CH.sub.3)--); and R.sup.2 is selected from the group consisting of hydrogen, halogen, hydroxy, C.sub.1-6 alkyl and C.sub.1-6 alkoxy; and salts thereof are inhibitors of the enzyme 5-lipoxygenase.
Processes for preparing the compounds of formula (I) and compositions containing them are also described.

REFERENCES:
Busch, Chem. Ber., 1903, 36, 3877-3890.
Heberlein, Annalen, 1898, 301, 58-69.

Affiliated with

Also associated with

Rating

Triazine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triazine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triazine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-55443