Triazine compounds as PI3 kinase and mTOR inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S113000

Reexamination Certificate

active

08039469

ABSTRACT:
Compounds of formula Iwherein:R1isand R2, R4, and R6-9are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.

REFERENCES:
patent: 1 020 462 (2000-07-01), None
patent: 1 020 462 (2004-02-01), None
Apr. 8, 2011 Non-Final Office Action issued in connection with U.S. Appl. No. 12/470,525.

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