Triarylcarboxylic acid derivative

Details Triarylcarboxylic acid derivative Triarylcarboxylic acid derivative

2006-10-06

2010-10-19

Puttlitz, Karl J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C548S146000, C548S373100, C549S029000, C546S318000, C514S277000, C514S362000, C514S363000, C514S438000

Reexamination Certificate

active

07816558

ABSTRACT:
Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general formula (I):wherein A is an optionally substituted aryl or heteroaryl, and B is an optionally substituted monocyclic heteroaryl; and a pharmaceutical composition comprising the same and a pharmaceutically acceptable carrier. The triarylcarboxylic acid derivative (I) exhibits potent xanthine oxidase inhibiting action and is therefore useful as a therapeutic agent for preventing or treating hyperuricemia, gout, inflammatory bowel disease, diabetic nephropathy and diabetic retinopathy.

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Database CAS citation 2006:196056 [retrieved Feb. 3, 2010] from STN; Columbus, OH, USA.
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