Tri-, tetra-, penta-, and polypeptides and their therapeutic use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 16, 514 18, 514 19, 514 20, 530329, 530330, 530331, 548537, A61K 3804, A61K 3807, C07K 504, C07K 706

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active

055894607

ABSTRACT:
The present invention discloses novel peptides utilized to treat patients suffering from depression. These novel peptides are modifications of the tripeptide hormone MIF, including modification of amino terminus residues, carboxyl terminus residues and internal residues, including addition and substitution of amino acid residues and modification of the peptide bonds and functional side groups of respective amino acid residues. The tri-, tetra-, penta-, and polypeptides of the present invention may be utilized alone or in combination to treat patients suffering from depression.

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