Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Ion exchange resin
Reexamination Certificate
2005-12-30
2010-10-12
Hartley, Michael G (Department: 1618)
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Ion exchange resin
Reexamination Certificate
active
07811555
ABSTRACT:
The present invention discloses a tri-branched copolymer comprising a hydrophobic domain, a hydrophilic domain, a biologically active moiety, and an alkyl core of 2 to 10 carbon atoms. The hydrophobic domain, the hydrophilic domain, and the biologically active moiety are separately linked to the alkyl core of 2 to 10 carbon atoms through three functional groups, wherein said three functional groups are independently the same or different. Preferably, the tri-branched copolymer is prepared through reversible addition fragmentation transfer (RAFT) polymerization and conjugation reactions. The present invention also discloses a coating composition for applying on at least a portion of one surface of an article. The coating composition comprises the inventive tri-branched copolymer. In another aspect, the present invention discloses an article having the inventive coating composition thereon. Preferably, the article is a medical device or a component of a medical device.
REFERENCES:
patent: 4973493 (1990-11-01), Guire
patent: 6238799 (2001-05-01), Opolski
patent: 6566506 (2003-05-01), Greenwald et al.
patent: 2003/0113477 (2003-06-01), Timmons et al.
patent: 2005/0266038 (2005-12-01), Glauser et al.
patent: WO 03/059973 (2003-07-01), None
patent: WO 03/078489 (2003-09-01), None
European Search Report dated Jun. 24, 2008 for EP Application No. EP 06256638.
Feng, Xiao-Shuang et al: “Synthesis of Amphiphilic Miktoarm ABC Star Copolymers by RAFT Mechanism Using Maleic Anhydride as Linking Agent” Macromolecules, vol. 35, No. 13, 2002, 4888-4893.
Shi, Peng-Jie et al., “Block and star block copolymers by mechanism transformation X . . . ”European Polymer Journal, 2004, 20, 1283-1290.
www.surmodics.com.
Cordis Corporation
Hartley Michael G
Rogers James W
LandOfFree
Tri-branched biologically active copolymer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tri-branched biologically active copolymer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tri-branched biologically active copolymer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4156283