Tri- and tetracyclic compounds

Details Tri- and tetracyclic compounds Tri- and tetracyclic compounds

1996-06-24

1998-09-22

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, 530317, 530327, 530328, 530330, 544 35, 544102, 549 16, 549388, A61K 3803, C07K 400

Patent

active

058113894

ABSTRACT:
There are described compounds of the formula ##STR1## Wherein the variables have been defined herein. The compounds are useful as research tools in the determination of biologically active peptides sequences and also potentially suitable as medicaments, some of them being useful in the prevention or control of the formation of blood platelet thrombi, and some compounds are useful as intermediates.

REFERENCES:
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patent: 4931429 (1990-06-01), Hanson et al.
Davies, et al., Biochemical Society Transactions, vol. 18, pp. 326-1328 (1990).
Diaz, H. and J. Kelly, Tetrahedron Letters, 32(41):5725-5728 (1991).
Ernest, I., et al., Tetrahedron Letters, 31(28):4011-4014 (1990).
Feigel, M., J. Am. Chem. Soc., 108:181-182 (1986).
Feigel, M., Liebigs Ann. Chem., pp. 459-468 (1989).
Rudinger, Peptide Hormones, pp. 1-7 (Jun. 1976).
The Merck Manual, 16th ed., Ch. 123, pp. 1451-1459. (1992).
Cook et al, "Fibrinogen as a major risk factor in cardiovascular disease", TIPS Reviews, vol. 11, pp. 444-445, Nov. 1990.

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