Tretinoin in a gel vehicle for acne treatment

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424 81, 424318, 424344, 424362, A61K 3120, A61K 3156

Patent

active

042475473

ABSTRACT:
An acne treatment gel composition, effective at low concentrations of tretinoin, is provided for topical application. The composition is highly effective in treating acne conditions and is capable of being stored without refrigeration for long periods of time without losing therapeutic effectiveness and while maintaining the uniformity and stability of the gel.

REFERENCES:
patent: 3729568 (1973-04-01), Kligman
patent: 3867533 (1975-02-01), Schmolka
Konig et al., Arzneimitt-Forsch, No. 8 (1974) 1184-1187.
Hopponen, Handbook of Non-Prescription Drugs, pp. 155-160 (1973).
Martin, Physical Pharmacy, pp. 623-627 (1962).
Physicians Desk Reference (PDR) 1968, pp. 1108 & 1214.

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