Treatments employing vasoconstrictive substances in combination

Details Treatments employing vasoconstrictive substances in combination Treatments employing vasoconstrictive substances in combination

1987-09-28

1990-12-18

Yasko, John D.

Surgery

Means for introducing or removing material from body for...

514930, A61N 130

Patent

active

049783327

ABSTRACT:
A pharmaceutical composition and method of treating cellular disorders involving abnormal solid cellular growths which comprises administering a pharmaceutical composition containing cytotoxic agents in combination with a vasoconstrictive drug. Enhanced effectiveness of the composition is observed, with reduced cytotoxic effects on cells distant from the site of introduction. Agents may be included to enhance therapeutic gain and reduce adverse affects to normal tissue.

REFERENCES:
patent: 3238101 (1966-03-01), Fruhstorfer et al.
patent: 3993754 (1976-11-01), Rahman
patent: 4177263 (1979-12-01), Rosenberg et al.
patent: 4186183 (1980-01-01), Steck et al.
patent: 4372949 (1983-02-01), Kodama
patent: 4536387 (1985-08-01), Sakamoto et al.
patent: 4558690 (1985-12-01), Joyce
patent: 4619913 (1986-10-01), Luck et al.
patent: 4710493 (1987-12-01), Landsberger
patent: 4738955 (1988-04-01), Landsberger
Krementz, et al., "Hyperthermic Regional Perfusion for Melanoma of the Limbs", Cutaneous Metanoma: Chapter 10, 1985, pp. 171-195.
Yatvin et al., "Design of Liposomes for Enhanced Local Release of Drugs by Hyperthermia", Science, vol. 202, 22, Dec. 1978, pp. 1290-1293.
Maugh, "Bound to Provoke a Reaction", Science, vol. 212, pp. 1128-1129, 1981.
Macek et al., Abstracts of Immunology, 4109, p. 1053.
Miyata et al., Cancer Research, vol. 43, pp. 4670-4675, Oct. 1983.
McLaughlin et al., Cancer Research, vol. 38, pp. 1311-1316, May, 1978.
Bier et al., Cancer, vol. 44, No. 4, pp. 1194-1200, Oct. 1979.

Affiliated with

Also associated with

Rating

Treatments employing vasoconstrictive substances in combination does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatments employing vasoconstrictive substances in combination , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatments employing vasoconstrictive substances in combination will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1423328