Treatment with dialdehydes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Aldehyde doai

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A61K 3111

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active

045699461

ABSTRACT:
Lower aliphatic dialdehydes have been found to react with human and other animal tissues in the living animal and that treatment of exposed tissue by topical application is useful in converting "wet" gangrene to "dry" gangrene, in forming a protective eschar for burned tissue, and for treating the raw, cut portions of the body during surgical excision of malignant tumors to prevent growth of implants resulting from dissemination of malignant cells during the excision. Threatment is generally by topical application of the dialdehyde diluted, typically, to 1 or 2 percent in a fluent carrier such as water or alcohol.

REFERENCES:
patent: 2801216 (1957-07-01), Yoder et al.
patent: 3983252 (1976-09-01), Buchalter
patent: 4082852 (1978-04-01), Heiss
Stock et al., Cancer Research, vol. 18, No. 8, Sep. 1958, pp. 49-53 and 182.
Leiter et al., Cancer Research, vol. 23, No. 8, Sep. 1963, pp. 1483-1495, 1498 and 1595.
Leiter et al., Cancer Research, vol. 23, No. 10, Nov. 1963, pp. 1930-1941, 1944, 1945 and 1984.

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