Treatment with anti-ErbB2 antibodies

Details Treatment with anti-ErbB2 antibodies Treatment with anti-ErbB2 antibodies

2007-07-20

2011-12-13

Dent, Alana Harris (Department: 1643)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S130100, C424S133100, C424S134100, C424S135100, C424S136100, C424S138100, C424S141100, C424S142100, C424S155100, C424S174100

Reexamination Certificate

active

08075892

ABSTRACT:
The present invention concerns the treatment of disorders characterized by the overexpression of ErbB2. More specifically, the invention concerns the treatment of human patients susceptible to or diagnosed with cancer overexpressing ErbB2 with a combination of an anti-ErbB2 antibody and a chemotherapeutic agent other than an anthracycline, e.g. doxorubicin or epirubicin. The invention further provides a method of treating cancer in a human patient comprising administering effective amounts of an anti-ErbB2 antibody and a cardioprotectant to the patient.

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