Treatment of Type II Herpes virus with ibuprofen

Details Treatment of Type II Herpes virus with ibuprofen Treatment of Type II Herpes virus with ibuprofen

1982-12-06

1987-10-20

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514532, A61K 3119, A61K 31235

Patent

active

047014709

ABSTRACT:
A process for treating Herpes Type II virus by the systemic administration or topical application of ibuprofen (p-isobutylhydratropic acid) or a salt or ester thereof. Dosage forms are also disclosed.

REFERENCES:
De Clercq, The Chemotherapy of Herpesvirus Infections with Reference to Bromovinyldeoxyuridine and Other Antiviral Compounds, Problems of Antiviral Therapy (Eds. C. H. Stuart-Harris and J. Oxford), 1983, pp. 295-315.
De Clercq, Antiviral Activity of 5-Substituted Pyrimidine Nucleoside Analogues, Pure & Appl. Chem., vol. 55, No. 4, pp. 623-636, 1983.
Hill, T. J., et al., The Lancet, pp. 397-398, Feb. 21, 1976.
Harbour, D. A., et al., J. of Gen. Virol, 41: 87-95 (1978).
Baker, D. A., et al., Program and Abstracts of the 21st Interscience Conference on Antimicrob. Agents & Chemotherapy, No. 204, Nov. 4-6, 1981.
Effect of Prostaglandin F2a (PGF) and Ibuprofen (IB) on Herpes Simplex Virus Type 2 (HSV2) Growth in Tissue Culture, David A. Baker et al., 28th Annual Meeting, Society for Gynecologic Investigation, Sci. Abstracts, St. Louis, Missouri, Mar. 18-21, 1981.
Chang, J of Infection, 1980, 2, pp. 374-376.
The Merck Index, 9th ed, 1976, Merck & Co. Inc., Rahway, N.J., p. 649 (No. 4796).

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