Treatment of tumors with thiazolidine-4-carboxylic acid

Details Treatment of tumors with thiazolidine-4-carboxylic acid Treatment of tumors with thiazolidine-4-carboxylic acid

1978-12-21

1983-05-17

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

A61K 31425

Patent

active

043840019

ABSTRACT:
Described herein is a method of treating malignant tumors or other cancerous conditions with thiazolidine-4-carboxylic acid, or pharmaceutically acceptable salts thereof, to arrest or retard the growth of the tumor. These agents induce reverse transformation in the tumor cells and restore to the cells the property of contact inhibition. A novel process for the preparation of the salts of thiazolidine-4-carboxylic acid is also described.

REFERENCES:
Connors et al., Biochem. Pharmacol, 1977, 26(24), pp. 2385-2391.

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