Treatment of sleep disorders with cholinesterase inhibitors

Details Treatment of sleep disorders with cholinesterase inhibitors Treatment of sleep disorders with cholinesterase inhibitors

2007-11-20

2007-11-20

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S462000, C514S468000, C514S510000

Reexamination Certificate

active

10915821

ABSTRACT:
The present invention is concerned with treatment of sleep disorders by administering a cholinesterase inhibitor, and in particular, by administering galantamine or a pharmaceutically acceptable salt thereof. Also in particular, cholinesterase inhibitors that are active at nicotinic receptors and that are selective for acetylcholinesterase over butylcholinesterase are used in treating sleep disorders.

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Timofeeva et al. “EEG Spectra, behavioral states, and motor activity in rats exposed to acetylcholinesterase inhibitor chlorpyrifos” Pharmacology, Biochemistry, and Behavior (2002) vol. 72, pp. 669-679.
Banji et al. “Emergent Complications Following Donepezil Switchover to Galantamine in THree Cases of Dementia With Lewy Bodies” The Journal of Neuropsychiatry and Clinical Neurosciences (2005) vol. 17, No. 4, pp. 552-555.
PCT International Search Report, dated Feb. 11, 2005, for PCT Int'l. Appln. No. PCT/US2004/026243.

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