Treatment of skin wounds using polyenylphosphatidylcholine...

Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations

Reexamination Certificate

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Details

C424S060000, C424S400000, C424S401000, C514S078000, C514S474000, C514S456000, C514S458000, C514S847000

Reexamination Certificate

active

06932963

ABSTRACT:
Polyenylphosphatidylcholine in combination with an alkanolamine are topically applied to treat skin wounds, promote healing, and minmize scar formation. Typical compositions contain from about 0.25% to about 12% of a polyenylphosphatidylcholine preparation obtained from natural sources such as soybean oil which contains at least about 25% by weight, preferably about 40% or more, dilinoeoylphosphatidylcholine, and from about 0.1% to about 10% by weight of an alkanolamine such as ethylaminoethanol, methylaminoethanol, dimethylaminoethanol, isopropanolamine, triethanolamine, isopropanoldimethylamine, ethylethanolamine, 2-butanolamine, choline, serine, or mixtures thereof. Dimethylaminoethanol is a particularly preferred alkanolamine. Tyrosine is an adjunct ingredient in many embodiments.

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Aleynik, S.I., et al.; Journal Invest. Medicine 47: 507-512 (1999).
Ibbotson, S.H., et al.; Journal Invest. Dermatology 112: 933-938 (1999).
European Search Report, Dec. 17, 2003.

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