Treatment of skin conditions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S317000, C514S543000, C549S441000, C549S440000, C549S430000, C549S429000

Reexamination Certificate

active

07122561

ABSTRACT:
The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also for treating skin cancer. The piperine and analogues or derivatives thereof may also be used to cosmetically promote or enhance the natural coloration of the skin.

REFERENCES:
patent: 4209445 (1980-06-01), Oediger et al.
patent: 4209446 (1980-06-01), Schulze et al.
patent: 27 57 483 (1979-06-01), None
patent: 0 650 728 (1995-05-01), None
patent: 6-336417 (1994-12-01), None
patent: 10130203 (1998-05-01), None
patent: WO 96/25939 (1996-08-01), None
patent: WO 00/02544 (2000-01-01), None
Chandhoke et al., “Interactive activity of Various species of piperidine . . . ”, Database CAPLUS, AN 1978:573794, (abstract only), Indian Journal of Pharmaceutical Sciences, 1978, vol. 40(4), pp. 113-116.
Banerji et al., “Sylvatine, New alkaide fromPiper sylvaticum”, Database CAPLUS, AN1973:442108(abstract only), Tetrahedron, 1973, vol. 29(7), pp. 977-979.
Gaind, K.N. et al; “Preservatives LX”; Database CA Online;Chemical Abstracts Service; Columbus, Ohio, US; retrieved from STN, Database Accession No. 83:72580, 1983.
De Paula, Vanderlucia F. et al; “Synthesis and insecticidal activity of a new amide derivatives of perine”;Pest Management Science; 56(2), pp. 168-174 (2000).
Bennett, D.C.; Cooper, P.; Hart , I.; (1987) A line of non-tumourigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth, International Journal of Cancer 39, 414-418.
Donato, S.; Kesavan, M.; Austin, S.; Mohan, K., and Rajagopalan, K.; (1990) Clinical trial of certain Ayurvedic medicines indicated in vitiligo, Ancient Sci. Life 9, 202-206.
Leung, A.Y.; (1985) Chinese Herbal Remedies, Publ. Wildwood House, London, UK, pp. 120-123.
Duke, J.A., and Ayensu, E.S. (1985) Medicinal Plants of China, vol. 2 Publ. Reference Publications Inc. Algonac, MI, USA, pp. 483-485.
Johri, R.K. and Zutshi U. (1992) An Ayurvedic formulation ‘Trikatu’ and its constituents, J. Ethnopharmacology 37, pp. 85-91.
Dymock W.; Warden, C.J. and Hooper, D. (1890) Pharmacographia Indica. Ed. Dymock W. Publ. K. Paul, Trench and Trubner, London, UK, pp. 166-181.
Kapoor, L.D. (1990) Handbook of Ayurvedic Medicinal Plants, Publ. CRC Press, Boca Raton, FL, USA, pp. 264-266.
The Wealth of India (1969), vol. VIII: Ph-Re. Publ. Publications and information directorate, CSIR, New Delhi, India, pp. 99-118.
Moss VNS (1953) Ayurvedic Flora Indica. Publ. not known, pp. 102-105.
Dutt, U.C. (1989) The Materia Medica of the Hindus, with a glossary of Indian Plants by KBL Sen and K.A. Sen, 2ndEdition, Publ. Mittal, Dehlhi, India, pp. 241-244.
Dash, V.B. (1983) A Handbook of Ayurveda. Publ. Concept Publishing, pp. 93-97.
Oriowo, M.A. (1982) Anti-inflammatory activity of piperonyl-4-acrylic isobutyl amide, Plant Medica 44, pp. 54-56.
Kirtikar, K.R. and Basu, B.D. (1935) Indian Medicinal Plants, 2ndedition, Eds. E. Blatter, J.F. Caius and K.S. Mhaskar, Publ. Lalit Mohan Basu, Allahabad, India, pp. 2128-2130 and 2133-2135.
Raman, A. and Lin, Z. (1996) ACTIVE Ingredients Conference Proceedings, Le Palais des Congres de Paris, France Nov. 13-14, 1996, Publ. Verlag fuer Chemische Industrie H. Ziolkowsky GmbH Augsburg, Germany, pp. 203-221.
Nadkarni, A.K. (1976) Dr. K.M. Nadkarni's Indian Materia Medica, vol. 1, Publ. Popular Parkashan, Bombay, India, pp. 960-972 and 1267-1270.
Parmar, V.S.; Jain, S.C.; Bisht, K.S. et al. (1997), Phytochemistry of the genusPiper(Review), Phytochemistry 46, pp 597-673.
Weatherall, D.J.; Ledingham, J.G.G; Warrell, D.A., eds (1996), Oxford Textbook of Medicine, 3rdedition Publ. Oxford University Press, Oxford, Section 23, pp. 3755-3759.
Raman, A.; Lin, Z.; Hoult, J.R.S., Identification of a phytochemical stimulant for the proliferation of mouse melanocytes in culture, J. Pharm. Pharmacol. 50 (Supplement), p. 247, 1998.
Lin, Z.; Donatein, P.; Raman, A.; Bennett, D.C. (1998) A naturally occurring growth promoter for human melanoblasts in culture J. Pharm. Pharmacol. 50 (Supplement), p. 218.
Lin, Z.; Hoult, J.R.S.; Bennett, D.C.; Raman, A. (1999) Stimulation of mouse melanocyte proliferation byPipernigrum L.fruit extract and its main alkaloid, piperine, Planta Medica 65, pp. 600-603.
WPI Abstract Accession N° 97 061723/06; Chemical Abstracts Accession N° 126: 94788, Derwent Abstract JP08310949 (YAKULT) Nov. 26, 1996 & JAPIO Abstract.
WPI Abstract Accession N° 96-318931/32; Derwent Abstract JP08143562 (CADILA) Jun. 4, 1996 & JAPIO Astract.
Raman, A.; Lin, Z. and Hoult, J.R.S. (1998), Identification of a phytochemical stimulant for the proliferation of mouse melanocytes in culture, Poster displayed at 135thBritish Pharmaceutical Conference, Eastbourne, U.K., Sep. 8-11, 1998.
Lin, Z.; Donatien, P.; Raman, A. and Bennett, D.C. (1998) Piperine, a naturally occurring growth promoter for human melanoblasts in culture, Poster displayed at 135thBritish Pharmaceutical Conference, Eastbourne, U.K., Sep. 8-11, 1998; and at 39thAnnual Meeting of the American Society of Pharmacognosy, Orlando, Jul. 19-24, 1998.
A. Raman, Z. Lin and J.R.S. Hoult, A mouse melanocyte proliferation stimulation fromPiper nigrum L., “2000 Years of Natural Product Research—Past, Present, Future”, Post displayed at Joint meeting of the American Society of Pharmacognosy, Association Francaise pour L'Enseignement et La Recherche en Pharmacognoise, Gesellschaft fuer Arzneipflanzenforschung and the Phytochemical Society of Europe, Amsterdam, The Netherlands, Jul. 26-30, 1999.
Lin, Z.X., Hoult, J.R.S., Raman, A. (1999) Sulphorhodamine B assay for measuring proliferation of a pigmented melanocyte cell line . . ., J. Ethnopharmacololgy 66, pp. 141-150.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Treatment of skin conditions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatment of skin conditions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of skin conditions will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3679820

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.