Treatment of retinal edema with brinzolamide

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514912, A61K 3141

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active

059488018

ABSTRACT:
Methods for preventing and treating retinal edema with brinzolamide are disclosed.

REFERENCES:
patent: 5240923 (1993-08-01), Dean et al.
patent: 5378703 (1995-01-01), Dean et al.
Miller, et al., "Active Transport of Ions Across Frog Retinal Pigment Epithelium," Experimental Eye Research, 25:235-248 (1977).
Marmor, et al., "Enhancement of Retinal Adhesion and Subretinal Fluid Resorption by Acetazolamide," Investigative Ophthalmology, 23 (1):121-124 (Jul., 1982).
Marmor, et al., "Pharmacologic Modification of Subretinal Fluid Absorption in the Rabbit Eye," Archives of Ophthalmology, 104:1674-1677 (Nov. 1986).
Cox, et al., "Treatment of Chronic Macular Edema With Acetazolamide," Archives of Ophthalmology, 106:1190-1194 (Sep. 1988).
Borhani, et al., "Vitreoretinal Toxicity of Acetazolamide Following Intravitreal Administration in the Rabbit Eye", Ophthalmic Surgery, 25 (3):166-169 (Mar. 1994).
Grover, et al., "Efficacy of Dorzolamide Hydrochloride in the Management of Chronic Cystoid Macular Edema in Patients with Retinitis Pigmentosa," The Journal of Retinal and Vitreous Diseases, 17(3):222-231 (1997).

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