Treatment of pulmonary hypertension

Details Treatment of pulmonary hypertension Treatment of pulmonary hypertension

1995-03-13

1997-07-22

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530324, 530325, 530326, 530328, 530309, C07K 14555, A61K 3816

Patent

active

056503954

ABSTRACT:
A method of lowering the pulmonary blood pressure of a subject suffering from pulmonary hypertension. The method includes administering to the subject an effective amount of a bombesin antagonist.

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Gosney et al., "Pulmonary Endocrine Cells in Pulmonary Arterial Disease", Arch Pathol Lab Med 113:337-341, Apr. 1989.
Heath et al., "Pulmonary Blood Vessels and Endocrine Cells in Subacute Infantile Mountain Sickness", Respiratory Medicine 83:77-81, 1989.
Kulik et al., "Pulmonary Vascular Effects of Bombesin and Gastrin-Releasing Peptide in Conscious Newborn Lambs", J. Appl. Physiol. Resp. Env. Exe. Phys. 55:1093-1097, 1983.
Obara et al., "The Effects of Various Peptides on the Isolated Pulmonary Artery", Peptides 10:241-243, 1989.
Heath et al., "Pulmonary Endocrine Cells in Hypertensive Pulmonary Vascular Disease", Histopathology 16:21-28 1990.

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