Treatment of psoriasis with nicotinamide analogues

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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A61K 31455

Patent

active

042580528

ABSTRACT:
A treatment to alleviate the symptoms of psoriasis consisting of topical application of a cream, lotion, ointment or gel containing as the principal active ingredient one or more nicotinamide analogues is disclosed. The therapeutic composition may include a single member of the above active ingredients present in a total amount of from 0.01 to 5 percent by weight of the total composition or a plurality thereof present in a preferred concentration range of from 0.02 to 2 percent by weight of the total composition. Topical application of the therapeutic composition in a cream, ointment, lotion, water or gel has been found to achieve from substantial to complete remissions of psoriasis in humans.

REFERENCES:
patent: 4082846 (1978-04-01), Clark
Chemical Abstracts, 66, 84597y (1967).
Chemical Abstracts, 67, 43650n (1967).
Chemical Abstracts, 75, 35630j (1971).

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