Treatment of psoriasis through down-regulation of the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S012200, C514S275000

Reexamination Certificate

active

07015199

ABSTRACT:
Topical agent formulations for the treatment of psoriasis containing epidermal growth factor (EGF) as the active agent. EGF precursors or biological equivalents can be used. The formulation can also contain an anti-inflammatory. The formulation can contain sulfadiazine.

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patent: 5130298 (1992-07-01), Cini et al.
patent: 6337320 (2002-01-01), Hersh et al.
patent: 0 339 905 (1989-11-01), None
Nanney et al. Modulation of Epidermal Growth Factor Receptors in Psoriatic Lesions During Treatment with Topical EGF. J. Invest. Dermatol. Mar. 1992, vol. 98, No. 3, pp. 296-301.
Phan et al. Association Between Pyoderma Gangrenosum And Psoriasis. Lancet. Aug. 24, 1996. vol. 348, p. 547.
Casaco et al. Topical Anti-Inflammatory Activity of Human Recombinant Epidermal Growth Factor. Skin Pharmacol. Appl. Skin Physiol. 1999. vol. 12, pp. 79-84.

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