Treatment of psoriasis and seborrheic dermatitis with imidazole

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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A61K 31415

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active

044915888

ABSTRACT:
A method is provided for treating psoriasis and seborrheic dermatitis in humans by oral administration of an effective, lesion reducing, amount of an imidazole antibiotic.

REFERENCES:
patent: 4172947 (1979-10-01), Warner et al.
patent: 4205071 (1980-05-01), Durant et al.
patent: 4358449 (1982-11-01), Heeres et al.
Chemical Abstracts 97:84718d (1982).
"Activation of the Alternative Pathway of Complement by Malassezia Ovalis (Pityrosporum Ovale)", Mycopathologia, vol. 70.3, pp. 187-191 (1980)--Article discusses a mechanism for seborrheic dermatitis.
"Effect of Topical Applications of Heavy Suspensions of Killed Malassezia Ovalis on Rabbit Skin," Mycopathologia, vol. 72, pp. 147-154, (1980)--Article discusses experimentation leading to an explanation of human psoriasis.
"Sabouraud and Rivolta were Right--Seborrheic Dermatitis is Microbial", Cosmetics and Toiletries, Aug. 1981--Article discusses a mechanism for seborrheic dermatitis.

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