Treatment of opiate addiction

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424260, A61K 31135

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active

039475921

ABSTRACT:
Addiction to opiate drugs, e.g., heroin, is treated by administering a beta-adrenergic-receptor-blocking drug, e.g. propranolol, which is found to block the rewarding and euphoric effects of the narcotic and to prevent the recurrence of hunger for the narcotic after withdrawal with methadone.

REFERENCES:
fennessy et al., Chemical Abstracts 74: 74888y 1971.
Dimezza et al., Chemical Abstracts 74: 2435x 1971.
Murmann et al., Chemical Abstracts 66: 1370g 1967.
Physicians Desk Reference (PDR) 25 Edition 1971 pp. 565-566.
Merck Manual 11th Edition 1966, pp. 133-134.
Current Therapy, Weiner, 1970, pp. 655-658.
Merck Manual 12th Edition, 1972, pp. 1409-1463.
The Pharmacological Basis of Therapeutics, 1966, pp. 302-303.

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