Treatment of obesity with an alpha-2-adrenergic agonist and a gr

Details Treatment of obesity with an alpha-2-adrenergic agonist and a gr Treatment of obesity with an alpha-2-adrenergic agonist and a gr

1990-09-10

1992-06-09

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 16, 514401, A61K 3700

Patent

active

051207133

ABSTRACT:
Obese patients may be effectively treated by cojointly administering an alpha-2-adrenergic agonist, such as clonidine, and a growth hormone releasing peptide, such as GHRH, to restore or substantially enhance growth hormone release in such patients.

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Ghigo, "Effects of the Enhancement of the Cholinergic Activity on Growth Hormone Secretion in Children: Clinical Implications", Recent Advances in Basic and Clinical Neuroendocrinology (eds. Casanueva and Dieguez), pp. 241-251, 1989, Excerpta Medica, Amsterdam.
Cordido et al., Chem. Abstracts 113:453 (Jul. 1990), abstract 21676S.

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