Treatment of obesity, diabetes and other symptoms of hypercortic

Details Treatment of obesity, diabetes and other symptoms of hypercortic Treatment of obesity, diabetes and other symptoms of hypercortic

1984-12-19

1987-05-19

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514866, 514909, A61K 3156

Patent

active

046668985

ABSTRACT:
Obesity, diabetes obesity syndromes and associated hypercorticoidism are treated with .alpha. and/or .beta.-etiocholanolone.

REFERENCES:
patent: 4507289 (1985-03-01), Coleman et al.
patent: 4518595 (1985-05-01), Coleman et al.
Fieser et al., "Steroids", (1959), p. 507 relied on.
Merck Index, (1976), Ninth Edition, Par. 676, p. 87 relied on.
"Steroids" by Fieser et al., pp. 504-505, (1959).
Louis F. Fieser and Mary Fieser, "Steroids", (1959), p. 506.
Douglas L. Coleman, "Antiobesity Effects of Etiocholanolones in Diabetes (db), Viable Yellow (A.sup.vy), and Normal Mice*", Endocrinology, vol. 117, No. 6, pp. 2279-2283.
D. L. Coleman, E. H. Leiter and N. Applezweig, "Therapeutic Effects of Dehydroepiandrosterone Metabolites in Diabetes Mutant Mice", Endocrinology, vol. 115, No. 1, pp. 239-243.

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