Treatment of muscular dystrophy with cord blood cells

Details Treatment of muscular dystrophy with cord blood cells Treatment of muscular dystrophy with cord blood cells

2002-07-23

2008-11-18

Kaushal, Sumesh (Department: 1633)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

C424S093200, C424S093210, C424S093300, C424S520000, C424S529000

Reexamination Certificate

active

07452529

ABSTRACT:
The invention features methods for treating a patient suffering from muscular dystrophy by administration of umbilical cord blood cells, e.g., by IV infusion.

REFERENCES:
patent: 5674750 (1997-10-01), Kraus et al.
patent: 5925567 (1999-07-01), Kraus et al.
patent: 6338942 (2002-01-01), Kraus et al.
patent: 2002/0051762 (2002-05-01), Raffii et al.
patent: WO 99/37751 (1999-07-01), None
Shon et al, Expert Opion. Biol. Ther. 4(1):1-9, 2004.
Meagher et al J Hematother. Stem Cell Res. 11(3):445-8, 2002.
Dell'Agnola et al Blood. 104(13):4311-8, 2004.
Chao et al, Hematology Am Soc Hematol Educ Program. 354-371, 2004.
Kong et al, Stem Cells 22:981-993, 2004.
Bretag, Nature. 450(7173):E23, 2007.
Kong et al. Human umbilical cord blood cells differentiate into muscle in sjl muscular dystrophy mice. Stem Cells. 22(6):981-93. 2004.
Beutler, “Gene Therapy,” Biol. Blood Marrow Transplant. 5:273-276 (1999).
Dao and Nolta, “Molecular Control of Cell Cycle Progression in Primary Human Hematopoietic Stem Cells: Methods to Increase Levels of Retroviral-Mediated Transduction,” Leukemia 13:1473-1480 (1999).
Gussoni et al., “Dystrophin Expression in themdxMouse Restored by Stem Cell Tranplantation,” Nature 401:390-394 (1999).
Koike, “Cryopreservation of Pluripotent and Committed Hemopoietic Progenitor Cells from Human Bone Marrow and Cord Blood,” Acta Paediatrica Japonica 25:275-282 (1983).
Lee et al., “Clonal Isolation of Muscle-Derived Cells Capable of Enhancing Muscle Regeneration and Bone Healing,” J. Cell Biol. 150:1085-1099 (2000).
Partridge et al., “Conversion ofmdxMyofibres from Dystrophin-Negative to -Positive by Injection of Normal Myoblasts,” Nature 337:176-179 (1989).
Torrente et al., “Intraarterial Injection of Muscle-Derived CD34+Sca-1+Stem Cells Restores Dystropin inmdxMice,” J. Cell Biol. 152:335-348 (2001).

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