Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1993-04-16
1995-04-18
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514170, 514178, 514182, A61K 3156, A61K 31595
Patent
active
054079276
ABSTRACT:
This invention relates to the treatment of mild depression in an aging patient population. The invention specifically relates to daily treatment with dehydroepiandrosterone to increase insulin-like growth factor-I serum levels and increase psychological well-being in these patients.
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Morales, A. J., et al., "Endocrine, Metabolic, and Quality of Life Effects of Three Months of Nightly Administration of Dehydroepiandrosterone (DHEA) to Adults Age 40-65," The Endocrine Society, 74th Annual Mtg., Abstract 841, pp. 262 (Jun. 24-27, 1992).
Morales, A. J., et al., "Serum Dehydroepiandrosterone (DHEA) and DHEA Sulfate (DS) Levels after Three Months of Administration of 50 Mg. Oral DHEA: Gender Difference," Society for Gynecologic Investigation, 39th Annual Mtg., Abstract 371, p. 294 (Mar. 18-21, 1992).
Clemmons, D. R., "Editorial: Role of Insulin-Like Growth Factor-1 in Reversing Catabolism," J. Clin. Endocrinology and Metabolism, 75(5):1183-1185 (1992).
Dusterberg, B., et al., "Plasma Levels of Dehydroepiandrosterone and 17.beta.-Estradiol after Intramuscular Administration of Gynodian-Depot.RTM. in 3 Women," Hormone Res., 17:84-89 (1983).
Morales Arlene J.
Yen Samuel S. C.
Criares T. J.
Henley III Raymond
The Regents of the University of California
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