Treatment of metallic surfaces using radiofrequency plasma depos

Details Treatment of metallic surfaces using radiofrequency plasma depos Treatment of metallic surfaces using radiofrequency plasma depos

1992-12-11

1994-08-09

Pal, Asok

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent structure

427470, 427 225, 424422, 424423, 530815, 530816, A61F 200, A61M 2300

Patent

active

053365186

ABSTRACT:
A treatment for metallic surfaces and devices having metallic surfaces is described. A film of heptafluorobutylmethacrylate (HFBMA) is applied to a surface by radiofrequency (RF) plasma deposition and subsequently treated with a biologically active agent. A water vapor RF plasma treatment of the HFBMA coating provides reactive groups thereon which can covalently bond to the biologically active agent. Alternatively, a spacer group can be bonded to the activated HFBMA and the biologically active agent can then be bonded to the spacer group. Devices coated according to the invention possess enhanced biocompatibility and the HFBMA coatings are durable even under severe crimping and expansion conditions.

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