Treatment of mammals suffering from damage to the central nervou

Details Treatment of mammals suffering from damage to the central nervou Treatment of mammals suffering from damage to the central nervou

1985-01-16

1988-05-03

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514263, 514269, 514284, 514288, 514401, 514414, 514634, 514964, 424449, 424457, 424468, A61K 3155, A61K 31495, A61K 3152, A61K

Patent

active

047420545

ABSTRACT:
A method, and compositions, for treating an animal with an injured spinal cord, causing loss to sensory function and motor control, to regain such function and control. The method comprises the administration of at least 1 .alpha..sub.2 -adrenergic receptor agonist or a serotonergic receptor agonist or a dopaminergic receptor agonist, and preferably a combination with an anti-desensitization agent, such as a xanthine, a .beta.-adrenergic receptor agonist or a vascular skeletal muscle dilator. The composition comprises at least 1 receptor agonist and a second compound acting in conjunction therewith or preventing desensitization thereof.

REFERENCES:
Goodman and Gilman, 6th ed., pp. 797-799, 632-639, 483-484.
Chem. Absts., 84:258z, 1976; 100:168888c, 1984; 101:2122u, 1984; 98:192204n, 1983.

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