Treatment of malignant tumor

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell

Reexamination Certificate

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Details

C424S093710, C424S423000, C378S065000, C607S088000

Reexamination Certificate

active

07541025

ABSTRACT:
The invention provides a technology which utilizes donor lymphocyte infusion and by which malignant tumor can be treated without causing such an adverse effect as graft versus host disease. Thus, a method for the treatment of malignant tumor is provided which comprises performing, in a patient requiring such treatment, donor lymphocyte infusion for the graft versus tumor reaction-based treatment of tumor and then performing radiation treatment, infusion of lymphocytes derived from the host or a third party identical in HLA type to the host, and intra bone marrow-bone marrow transplantation using bone marrow cells derived from the host or a third party identical in HLA type to the host, for the prevention and treatment of the graft versus host disease induced by the donor lymphocyte infusion.

REFERENCES:
patent: 5229109 (1993-07-01), Grimm et al.
patent: 5514364 (1996-05-01), Ildstad
patent: 6383481 (2002-05-01), Ikehara et al.
patent: 6558662 (2003-05-01), Sykes et al.
Dictionary of Immunology, 1985 Herbert et al, Ed.s, p. 8 “alloantigen”.
Ashkenasy (Stem Cells, 2002, vol. 20, pp. 86-93).
Matthes-Martin et al (Bone Marrow Transplantation, 2000, vol. 26, pp. 377-382).
Roush et al (Transfusion Medicine Reviews, 2002, vol. 16, pp. 161-176).
abstract of Ballester et al (Blood, vol. 100, No. 11, abstract No. 5198).
Kushida et al (Blood, 2001, vol. 97, pp. 3292-3299).
Sherer and Shoenfeld (Bone Marrow Transplantation, 1998, vol. 22, pp. 873-881).
Drobyski et al (Journal of Immunology, 2000, vol. 165, pp. 1634-1640).
Yamamoto et al,Blood, 88(2):445-454 (1996).
Carella et al,Bone Marrow Transplantation, 25:345-350 (2000).
Di Nicola et al,Blood, 99(10):3838-3843.
Martino et al,Blood, 100(6):2243-2245 (2002).
Billiau et al,Blood, 100(5):1894-1902 (2002).

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