Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-07-20
1997-11-04
Kunz, Gary L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 2761, 536 2762, 536 2763, 536 277, A61K 3170, C07H 19167
Patent
active
056839898
ABSTRACT:
The present invention relates to compounds of formula I ##STR1## wherein X is amino, C.sub.1-6 -alkylamino, di-C.sub.1-6 -alkylamino;
REFERENCES:
patent: 3590029 (1971-06-01), Koch et al.
patent: 3901876 (1975-08-01), Vorbruggen et al.
patent: 4341769 (1982-07-01), Marumoto et al.
patent: 4600707 (1986-07-01), Patt
patent: 4657897 (1987-04-01), Bristol et al.
patent: 4657898 (1987-04-01), Bristol et al.
patent: 4704381 (1987-11-01), Schaumann et al.
patent: 5043325 (1991-08-01), Olsson et al.
patent: 5484774 (1996-01-01), Lau et al.
Olsson et al. "N.sup.6 -Substituted N-Alkyladenosine-5'-uronamides: Bifunctional Ligands Having Recognition Groups for A1 and A2 Adenosine Receptors," J. Med. Chem., 29(9), 1683-1689 (1986).
Cadogan et al., "On the Formation of Benzenediazonium Chloride in Gomberg-Hey Type Reactions of Diazonium Salts with Bromotrichloromethane, Carbon Tetrachloride, and Chloroform. The Solution of a Long-standing Mechanistic Puzzle," J. Chem. Soc. Chem. Comm., 1976, 851-852.
Vorbruggen et al., "Einfach neue Synthese von N.sup.6 -Substituierten Adenosinen und Adeninen sowie ihrer 2-Amino-and 2-Hydroxyderivate," Liebigs Ann. Chem., 1976, 745-761.
Nair et al.(I), "Utility of Purinyl Radicals in the Synthesis of Base-Modified Nucleosides and Alkylpurines: 6-Amino Group Replacement by H, CL, Br, and I," J. Organic Chem., 45(20), 3936-3974 (1980).
Nair et al. (II), "Modification of Nucleic Acid Bases via Radical Intermediates: Synthesis of Dihalogenated Purine Nucleosides", Synthesis, 1982, 832-834.
Koster et al., "Some Improvements in the Synthesis of DNA of Biological Interest," Nucleic Acids Research, Symposium Series No. 7, IRL Press Ltd., 1980, London, U.K., pp. 39-60.
Goodman, "Chemical Syntheses and Transformations of Nucleosides," Ch. 2 in Basic Principles in Nucleic Acid Chemistry, Academic Press, New York, 1974, pp. 94-208, only pp. 153-154 and subsequent pages with reference citations supplied.
Hansen Anker Jon
Knutsen Lars Jacob Stray
Lau Jesper
Sheardown Malcolm
Crane L. Eric
Kunz Gary L.
Lambiris, Esq. Elias J.
Novo Nordisk A S
Zelson Esq. Steve T.
LandOfFree
Treatment of ischemias by administration of 2,N.sup.6 -substitut does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of ischemias by administration of 2,N.sup.6 -substitut, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of ischemias by administration of 2,N.sup.6 -substitut will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1833129