Treatment of inflammatory diseases including psoriasis

Details Treatment of inflammatory diseases including psoriasis Treatment of inflammatory diseases including psoriasis

2011-01-04

2011-01-04

Hui, San-ming (Department: 1628)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

07863429

ABSTRACT:
Inhibitors of integrin-linked kinase (ILK) are used in the treatment of inflammatory disease, including cutaneous inflammatory diseases, such as psoriasis, scleroderma, systemic lupus erythematosus and atopic dermatitis.

REFERENCES:
patent: 5378725 (1995-01-01), Bonjouklian et al.
patent: 6001622 (1999-12-01), Dedhar et al.
patent: 6046224 (2000-04-01), Natarajan et al.
patent: 6214813 (2001-04-01), Zhang et al.
patent: 6291447 (2001-09-01), Andersen et al.
patent: WO 94/21781 (1974-09-01), None
patent: 96/00760 (1996-05-01), None
patent: WO 96/36642 (1996-11-01), None
Robbins Pathological Basis of Disease, 1994, W.B. Saunders Company, 5th edition, pp. 75-84.
Zhang et al. (Up-regulation of phophatidylinositol 3-kinase in psoriatic lesion, 1999, Chinese Medical Journal, vol. 112, iss. 12, pp. 1097-1100).
Dedhar, Shoukat, “Integrin Mediated Signal Transduction In Oncogenesis: An Overview,”Cancer and Metasis Reviews(1995) vol. 14:165-172.
Dedhar and Hannigan, “Integrin Cytoplasmic Interactions and Bidirectional Transmembrane Signaling,”Current Opinion Cell Bio.(1996) vol. 8:559-657.
Gimond et al.,Exp. Cell Res.,(1995) vol. 216:232-235.
Hannigan et al., “Regulation of Cell Adhesion and Anchorage Dependent Growth By A New Betal Integrin Linked Protein Kinase,”Nature(1996) vol. 379:91-96.
Hannigan et al., “Overexpression of A Novel Integrin Linked Kinase (ILK) Induces a Transformed Phenotype and Cyclin D1 Expression,”Molecular Biology of the Cell(Nov. 1995) vol. 6:2244 XP000673935.
Hannigan et al., “Cloning of a Novel Protein Kinase Associated With Beta 1 Integrin Cytoplasmic Tails,” 86thAnnual Meeting of the American Association for Cancer Research(Mar. 1995) p. 361, XP000673939.
Kappel, Catherine A. et al., (1992)Current Opinion in Biotechnologyvol. 3:548-553.
Lin, Tsung H. et al., “Integrin-Mediated Tyrosine Phosphorylation and Cytokine Mesage Induction in Monocytic Cells,”The Journal of Biological Chemistry(Jul. 7, 1995) vol. 270, No. (27):16189-16197.
Jacq et al., (1994)Cellvol. 79, No (1):107-117.
Miyamoto, Shingo et al., “Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function,”Science(Feb. 10, 1995) vol. 267:883-885.
Palmiter er al., (Nov. 1983) Science vol. 222:809-814.
Pursel, V.G. et al., (1990)J. Reprod. Fert., Suppl.vol. 40:235-245.
Morino et al., “Matrix-Integrin Interaction Activates the Mitogen Activated Protein Kinase p44erk, 1 and p42erk-2,”J. Biological Chemistry(1995) vol. 270:269-273.
Rosales, Carlos et al., “Signal Transduction By Cell Adhesion Receptors,”Biochimica et Biophysica Acta(1995) vol. 1242:77-98.
Lipfert. et al., (1992)J. Cell Biol.vol. 199:905-912.

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