Treatment of hypertension with fluoxetine and l-5-hydroxytryptop

Details Treatment of hypertension with fluoxetine and l-5-hydroxytryptop Treatment of hypertension with fluoxetine and l-5-hydroxytryptop

1980-10-31

1982-05-11

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424309, 424319, 424327, 424330, A61K 3140, A61K 31135, A61K 31195, A61K 3124, A61K 3115

Patent

active

043293565

ABSTRACT:
Fluoxetine alone or a combination of fluoxetine and l-5-hydroxytryptophan, preferably also with a peripheral decarboxylase inhibitor, is administered to hypertensive mammals to lower blood pressure.

REFERENCES:
patent: 4018895 (1977-04-01), Molloy
patent: 4035511 (1977-07-01), Messing
patent: 4194009 (1980-03-01), Molloy
Fuller, Res. Comm. in Chem. Path. & Pharm., vol. 10, No. 1, Jan. 1975, pp. 193-196.
Fuller, Life Sci., vol. 25, 1979, pp. 1237-1242.
Antonaccio et al., J. Pharm. Pharmac., vol. 25, 1973, pp. 495-497.
Henning et al., Acta Pharmacol. et Toxicol., vol. 29, 1971, pp. 145-154.
Krulich, Life Sci., vol. 17, 1975, pp. 1141-1144.
Fuller et al., Fed. Proc., vol. 36, No. 8, Jul. 1977, pp. 2154-2158.

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